Devonte Brown went 6 of 8 from 3-point range and scored a career-high 24 points on Saturday to lead Indiana State to a 72-61 win over Loyola of Chicago.
Rayvonte Rice scored 21 points as the Illini improved to 5-0.
Jake Odum scored 18 points as second-seeded Indiana State knocked off No. 10 seed Loyola of Chicago 75-62 in a Missouri Valley Conference quarterfinal on Friday.
Justin Gant had 18 points and 11 rebounds Sunday and Indiana State defeated Illinois State 77-75 in the Missouri Valley Conference opener for both teams.
It was just the second time in 13 games DePaul has lost against Indiana State, the last time was in 1979,