(WSCR) Behind back-up quarterback Jason Campbell, starting in place of a concussed Jay Cutler, the Bears will march to San Francisco for a key NFC matchup against the 49ers.

Can Campbell lead the Bears to a victory? Will the defense be able to stop Frank Gore?

Check out 670 The Score’s Laurence Holmes as he gives you his “What To Watch For” in the video below!

For game-day updates, follow Laurence on Twitter @LaurenceWHolmes.