Chicago (CBS) — The topic of abortion was front and center on the streets of Chicago Sunday as both sides made their voices heard.

Thousands of pro-life activists from around the Midwest marched through downtown during the 46th annual March for Life.

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This year’s theme is “Unique from Day One: Pro-Life Is Pro-Science.”

Organizers say 76 Marches for Life took place around the United States.

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Hundreds of pro-choice supporters took to the same streets with signs for the March for Abortion Rights.

Pro-choicers held signs supporting a woman’s right to choose.

Organizers also reiterated women should not have to apologize if they choose to have an abortion.

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Both marches coincide with next week’s anniversary of the Roe v. Wade decision by the U.S. Supreme Court, which legalized abortion in 1973.