(AP) — The Chicago White Sox started their three-game series at Fenway Park coming off of a stretch that saw them lose four of five games. But they have the chance to leave Fenway Park with a three-game sweep of the Red Sox.

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Gavin Floyd is hoping for a similar effect when he faces the Boston Red Sox.

Floyd will try to continue his dominance of the Red Sox and lead the White Sox to a three-game sweep and their seventh straight road win in the series Wednesday afternoon.

Chicago (26-31) came into Boston having lost three straight on their 10-game trip and with manager Ozzie Guillen trying to clarify some controversial comments he made before a 13-4 drubbing in Toronto on Sunday.

The White Sox have put all of that behind them by putting 17 runs on the board in consecutive wins over the Red Sox (30-25). Chicago jumped out to a 10-1 lead Tuesday, then held on for a 10-7 win behind Alexei Ramirez’s career high-tying four hits and three RBIs.

The White Sox, who have taken 12 of their last 14 overall meetings with Boston, now have a chance to match their seven-game run at Fenway from July 12, 1958-May 14, 1959.

Floyd (5-5, 3.69 ERA) has dropped three straight on the road, though he pitched well enough to win last Wednesday, limiting Texas to two runs – one earned – over seven innings but getting saddled with a 2-1 loss.

“Our offense is good enough to put up a lot of runs,” Floyd said. “I just want to keep the team in the game.”

Floyd was originally scheduled to pitch Tuesday but was pushed back a day after taking the loss in relief during a 14-inning game Saturday in Toronto.

The right-hander is 4-0 with a 2.81 ERA in five career starts against Boston, and has a 1.69 ERA in his last four. He gave up one run and five hits over six innings of a 3-1 win at Fenway last Sept. 4.

He will be opposed by Tim Wakefield (2-1, 4.14), who is seeking his third victory in as many outings. The 44-year-old knuckleballer, who gave up two runs over a season-high seven innings of Friday’s 6-3 win in Detroit, will now try to keep his team from its first four-game skid since opening the season 0-6.

“You know, I’m just doing what I can to help us win games,” Wakefield told the Red Sox’s official website. “I was asked to fill a role here, and I’m trying to do the best that I can.”

Wakefield, who is five wins shy of 200 for his career, is 3-8 with a 4.84 ERA in his last 12 starts against the White Sox with the most recent Sept. 5, 2009.

David Ortiz is one Boston player enjoying this series. He’s 4 for 7 through the first two games, including a three-run homer during Tuesday’s failed comeback attempt. The Red Sox designated hitter batted .342 with 10 homers in May.

He is 5 for 17 with two home runs lifetime against Floyd.

Ramirez, hitting .368 with 16 RBIs in his last 13 games, is 1 for 9 versus Wakefield.

Copyright 2010 by STATS LLC and The Associated Press. STATS LLC and The Associated Press contributed to this article. Any commercial use or distribution without the express written consent of STATS LLC and The Associated Press is strictly prohibited.

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